Fc receptor - Wikipedia
WEBIn immunology, an Fc receptor is a protein found on the surface of certain cells – including, among others, B lymphocytes, follicular dendritic cells, natural killer cells, macrophages, neutrophils, eosinophils, basophils, human platelets, and mast cells – that contribute to the protective functions of the immune system.
Fcγ receptors as regulators of immune responses - Nature
WEBHuman and mouse Fc receptors for IgG (FcγRs) can be distinguished by their affinity for the antibody Fc-fragment and by the signalling pathways they induce.
Frontiers | Understanding Fc Receptor Involvement in …
WEBApr 11, 2019 · Fc receptors (FcRs) belong to the ITAM-associated receptor family. FcRs control the humoral and innate immunity which are essential for appropriate responses to infections and prevention of chronic inflammation or auto-immune diseases.
Fc Receptors in Immune Responses - PMC - National Center for ...
WEBNov 28, 2014 · Leino L., Sorvajarvi K., Katajisto J., Laine M., Lilius E.M., Pelliniemi T.T., Rajamaki A., Silvoniemi P., Nikoskelainen J. Febrile infection changes the expression of IgG Fc receptors and complement receptors in human neutrophils in vivo.
The role of IgG Fc receptors in antibody-dependent enhancement
WEBAug 11, 2020 · Fc–Fcγ receptor (FcγR) interactions drive pleiotropic effector functions that limit viral replication and provide potent antiviral protection. a | clearance of IgG opsonized virions.
The Diverse Functions of the Ubiquitous Fcγ Receptors and Their …
WEBFeb 20, 2020 · The γ subunit of the immunoglobulin Fc receptor (FcRγ) is a key component of discrete immune receptors and Fc receptors including the FcγR family. Furthermore, FcγRs exert a key role in terms of crosslinking the innate and adaptive workhorses of immunity.
Type-I and Type-II Fc receptors regulate innate and adaptive …
WEBType-I Fc-receptors regulate the function of anti-viral, anti-tumor, and immunomodulatory antibodies in vivo. Type-I FcRs play crucial roles during humoral immune responses against foreign pathogens or epitopes expressed by malignant cells during tumor immunity.
Understanding Fc Receptor Involvement in Inflammatory Diseases…
WEBApr 12, 2019 · Here, we review FcR involvement in pathologies leading notably to altered intracellular signaling with functionally relevant consequences to the host, and targeting of Fc receptors as therapeutic approaches.
Roles of Fc receptors in autoimmunity - Nature
WEBAug 1, 2002 · The receptors for the Fc of immunoglobulins, Fc receptors (FcRs), link the humoral and cellular branches of the immune system, and they have important functions in the activation and down ...
Fc Receptors: Introduction - Hogarth - 2015 - Wiley Online Library
WEBOct 26, 2015 · The receptors for immunoglobulins we know as Fc receptors (FcR), which are primarily expressed on/in innate immune cells, provide the antibodies – the archetypal mediators of the adaptive immunity – with cell-based systems of …