Cytokine Regulation and Function in T Cells - PubMed
WEBApr 26, 2021 · T lymphocytes, the major effector cells in cellular immunity, produce cytokines in immune responses to mediate inflammation and regulate other types of immune cells.
The adaptive cellular immune response: T cells and cytokines
WEBJan 30, 2023 · T cells regulate the activities cells participating in immune responses. They provide help for antibody production by B cells, and they are also the effectors of antigen-specific cell-mediated immunity (CMI).
T Cells: Types and Function - Cleveland Clinic
WEBT cells are a type of white blood cell called lymphocytes. They help your immune system fight germs and protect you from disease. There are two main types. Cytotoxic T cells destroy infected cells. Helper T cells send signals …
Cytokine Regulation and Function in T Cells - Annual Reviews
WEBMechanisms exist to prevent cytokine production by T cells to maintain immune tolerance to self-antigens, some of which may also underscore immune exhaustion in the context of tumors. Understanding cytokine regulation and function has offered innovative treatment of many human diseases.
T cells in health and disease - Nature
WEBJun 19, 2023 · In this review, we summarize the current understanding of T cell development, CD4+ and CD8+ T cell classification, and differentiation in physiological settings.
T cell subsets and their signature cytokines in autoimmune and ...
WEBOct 14, 2016 · This article will review the different Th subsets in terms of cytokine profiles, how these cytokines influence and shape the immune response, and their relative roles in promoting pathology in autoimmune and inflammatory diseases.
A guide to cancer immunotherapy: from T cell basic science to …
WEBMay 20, 2020 · The T lymphocyte, especially its capacity for antigen-directed cytotoxicity, has become a central focus for engaging the immune system in the fight against cancer.
T cell receptor and cytokine signal integration in CD8 - Nature
WEBJan 13, 2020 · Identification of molecules regulating mature T cell responses to low-affinity ligands and cytokines is of clinical importance, as these can be targeted to modulate T cell activation during...
T cell subsets and their signature cytokines in autoimmune and
WEBThis article reviews the different Th subsets in terms of cytokine profiles, how these cytokines influence and shape the immune response, and their relative roles in promoting pathology in autoimmune and inflammatory diseases.
Cytokines, Transcription Factors, and the Initiation of T-Cell ...
WEBT-cell development is initiated from the subpopulation that lacks the expression of both CD4 and CD8, thus called double-negative (DN) cells, which then become CD4 + CD8 + double-positive (DP) and subsequently differentiate into …