New Drug Molecule Offers Hope for Treating Early-Onset …
WEB1 day ago · New research suggests that a novel drug molecule could lead to treatments preventing Parkinson’s disease in younger patients. The study, led by Kalle Gehring at McGill University, focuses on a Biogen-developed compound that reactivates the parkin protein, crucial for clearing damaged mitochondria. This approach could pave the way for ...
ALS Fingerprint Test Shows 98% Accuracy in Preclinical Study ...
WEBSep 13, 2024 · The eight microRNA ALS fingerprint accurately detects ALS with as high as 98% accuracy and can separate ALS from PLS and PD. To confirm its reliability, the biomarker was tested across four different patient groups, in two labs, with various technicians and collection methods. The ALS fingerprint consistently produced reliable …
RNA-Seq: Basics, Applications and Protocol - Technology Networks
WEBApr 6, 2018 · RNA-seq (RNA-sequencing) is a technique that can examine the quantity and sequences of RNA in a sample using next-generation sequencing (NGS). It analyzes the transcriptome, indicating which of the genes encoded in our DNA are turned on or off and to what extent. Here, we look at why RNA-seq is useful, how the technique works …
Neuroimaging Techniques and What a Brain Image Can Tell Us
WEBJul 7, 2022 · Neuroimaging is a discipline that deals with the in vivo depiction of the structure, function and pharmacology of the central nervous system (CNS), particularly our brain, in a noninvasive manner. 1, 2 The past two decades have witnessed remarkable strides in the development of new anatomical and functional imaging techniques that …
Blood Nanoparticles With Potential To Transform Cancer Diagnosis ...
WEBAug 19, 2024 · The research team named these RNA molecules "EV-UGRs" (short for Extracellular Vesicles-Associated Unannotated Genomic Regions) after discovering them in the blood and urine of prostate cancer patients. UGRs are often referred to as the “dark matter” of the human genome. They are believed to be crucial for controlling how genes …
Alzheimer’s Expert: What Does the Future of Dementia Diagnosis …
WEB1 day ago · While several types of dementia exist – such as vascular dementia, frontotemporal dementia and Lewy body dementia – the most common form is Alzheimer’s disease (AD), which accounts for 60–80% of cases. A hallmark of AD is the accumulation of abnormal amyloid beta (Aβ) proteins in the brain, which form plaques and disrupt healthy ...
Understanding Single-Cell Sequencing, How It Works and Its …
WEBJan 20, 2022 · Traditional next-generation sequencing (NGS) examines the genome of a cell population, such as a cell culture, a tissue, an organ or an entire organism.Its output is the “average genome” of the cell population. On the other hand, single-cell sequencing measures the genomes of individual cells from a cell population. 5 Nowadays, traditional …
One Step Closer to a System That Can Detect Any Virus
WEBDec 22, 2023 · To bridge this gap, in 2015, scientists at the Center for Infection and Immunity (CII) at Columbia University Mailman School of Public Health introduced a powerful NGS-based screening and surveillance system called VirCapSeq-VERT which can detect any virus that can potentially infect humans, known or unknown, with greater …
Mapping Development and Disease With Spatial Biology …
WEB3 days ago · Spatial biology has an integral role in understanding biological processes involving the activation of genes in specific locations and tissue reorganization, such as those driving embryonic development and many diseases. While traditional single-cell genomic and transcriptomic studies enable researchers to investigate every cell within …
Clearer Diagnostics, Improved Chances: The Big-Picture Impacts of ...
WEBFeb 14, 2024 · Explore how innovations in the cancer diagnostic space, particularly those focusing on simple but effective diagnostic methodologies, could make cancer screening and early detection more straightforward, improving access and outcomes for patients.
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