Stepney is an area in London, England located in the London Borough of Tower Hamlets. It is in East London and part of the East End. Stepneā¦Stepney is an area in London, England located in the London Borough of Tower Hamlets. It is in East London and part of the East End. Stepney is no longer officially defined, and is usually used to refer to a relatively small area. However, for much of its history the place name applied to a much larger manor and parish. Stepney Green is a remnant of a larger area of Common Land formerly known as Mile End Green.