For the third time in as many tries, Notre Dame got off to a slow start at home in Notre Dame Stadium. After a fumbled opening kickoff followed by a poor quick change defensive series which allowed Louisville to quickly grab momentum and a 7-0 lead, Notre Dame had options.

Riley Leonard threw two touchdown passes and ran for another, and No. 16 Notre Dame capitalized on No. 15 Louisville’s first three turnovers of the season to hold on for a 31-24 victory Saturday.

Louisville vs Notre Dame football prediction, odds and how to watch college football Week 5 game. Here's what to know about Louisville football.

The No. 15 Louisville Cardinals (3-0) travel to South Bend to take on the No. 16 Notre Dame Fighting Irish (3-1) in a ranked matchup with big stakes for both sides. It’s a rematch of the game that last year effectively ended Notre Dame’s 2023 College Football Playoff hopes as the Cardinals handed the Irish their second loss of the season.

No. 14 Notre Dame is never going to live down this month’s loss to Northern Illinois, especially with the Huskies dropping two of three since the upset in South Bend. But the College Football Playoff math still favors the Fighting Irish: win out and you’re (very likely) in the 12-team field.

Yahoo Sports' Caroline Fenton and Jason Fitz react to the Fighting Irish's 31-24 win over the Cardinals and whether they are impressed by Notre Dame's second win over a ranked opponent this season. Subscribe to the “College Football Power Hour” podcast on Apple Podcasts,

Riley Leonard passed for two touchdowns and ran for one more, and No. 16 Notre Dame held off No. 15 Louisville for a 31-24 win on Saturday afternoon in South