Under conditions of low unfolded protein stress, the lumenal domains of PERK and IRE1 are in complex with the endoplasmic reticulum chaperone BiP, whose binding correlates with the inactive state ...

In response to ER stress, eukaryotic cells increase transcription of genes encoding ER-resident chaperones such as BiP/GRP78 and GRP94; this induction system is termed the unfolded protein ...

The “Best Interests Procedure” (BIP) describes UNHCR’s case management framework for asylum-seeking and refugee children. BIP includes the key steps of child protection case management as well as ...

University Health — which includes two hospitals — had a median time spent in the ER of six hours from October ... doctors and nurses tend to experience more stress and distraction, and ...

In a central Phoenix emergency room, nurse Mindy Turner picked up a ringing phone. It was a Friday afternoon in July, another hot weekend beckoning. But at Valleywise hospital on east Roosevelt ...

Some stress can be healthy and even motivating under the proper circumstances, but often stress is overwhelming and can lead to other issues. "Stress is there for a reason. It's there to help ...

High cortisol levels caused by stress can affect the digestive and nervous systems, leading to weight loss. If you unintentionally lose more than 5% of your bodyweight, it is recommended that you ...

Is there too much stress in your life? To find out, take this quiz, adapted from a scale developed by Peter Lovibond at the University of New South Wales. For the first 16 questions, please indicate ...

Stress is our body’s response to any demand, challenge or change that disrupts our usual norms, explains Adrian Jacques ...

Investment fund Maelstrom has awarded a grant to a Bitcoin Core developer for maintaining the Bitcoin Improvement Proposals (BIP) repository. The grant was given to Jon Atack, a senior developer ...