It’s unclear how many people are taking rapamycin for its anti-aging properties since the drug is typically taken off-label ...

Rapamycin is typically prescribed to organ transplant patients to suppress their immune systems. But many scientists and ...

A study reveals that human embryos may possess a dormancy capability similar to that observed in many other mammals, opening ...

The epilepsy medication sodium valproate is linked to developmental problems in fetuses, but lab studies may now have found a ...

The drug blocks the activity of a protein known as mammalian target of rapamycin (mTOR), which promotes proliferation through the activation of proteins such as S6 kinase. Although the mTOR ...

Continued use of systemic glucocorticoids, a calcineurin inhibitor (tacrolimus or cyclosporine), or a mammalian target of rapamycin (mTOR) inhibitor (sirolimus or everolimus) that the patient was ...

Purpose: The mechanism of action and pharmacokinetics of sirolimus when used as part of a drug-eluting stent (DES) and the efficacy and cost of using DESs versus bare-metal stents are discussed.

Anti-aging enthusiasts are embracing the promise they believe exists in the immune-suppressing drug rapamycin, a generic ...

A recent study published in the Journal of Psychopharmacology suggests that psilocybin, the psychoactive compound found in ...

2010;67(24):2095-2106. Temsirolimus is primarily metabolized by the cytochrome P-450 (CYP) 3A4 isoenzyme to five major metabolites, with sirolimus being the principal active metabolite.

For a group of people trying to slow aging, a small weekly dose of rapamycin is part of their strategy. They use the drug off ...