Overall, the new immunosuppressive agents tacrolimus, sirolimus and MMF have significant clinical roles in solid organ transplantation, but they have narrow therapeutic ranges and numerous toxicities.

Tacrolimus is used with other medications ... or heart transplant. Sirolimus is used with other medications to prevent rejection of a kidney transplant. Azathioprine is used to prevent organ ...

In autosomal dominant polycystic kidney disease (ADPKD) and its common extrarenal manifestation polycystic liver disease (PLD), cyst development is caused by epithelial cell proliferation that is ...

sirolimus, everolimus) may increase risk of thrombotic microangiopathy. Concomitant strong CYP3A4 inhibitors/inducers or substrates: must adjust dosing regimen, closely monitor tacrolimus blood ...

sirolimus, everolimus) may increase risk of thrombotic microangiopathy. Concomitant strong CYP3A4 inhibitors/inducers or substrates: must adjust dosing regimen, closely monitor tacrolimus blood ...

Ipriflavone can block part of the process that leads to bone loss. Ipriflavone can block part of the process that leads to bone loss. A bone disease that can cause pain (Paget disease). Early ...

Study reviews transplant-acquired food allergies, focusing on pediatric patients, particularly liver transplant recipients.

Continued use of systemic glucocorticoids, a calcineurin inhibitor (tacrolimus or cyclosporine), or a mammalian target of rapamycin (mTOR) inhibitor (sirolimus or everolimus) that the patient was ...

The full CMI on the next page has more details. If you are worried about using this medicine, speak to your doctor or pharmacist. ISOPTIN injection contains the active ingredient verapamil ...

Arteries and veins are the major blood vessels in your body. Arteries carry blood from the heart, while veins carry blood to the heart. Arteries and veins are two of the body’s main types of ...

Because of what SSDs are, solid-state drives (SSDs) are a core component of any modern PC, whether it’s a traditional SATA SSD or a more modern NVMe drive. Knowing the difference between these ...

This article reviews the role of, and factors pertinent to, TDM of the newer immunosuppressive agents tacrolimus (FK-506), sirolimus (rapamycin) and mycophenolate mofetil (MMF) [see Differential ...