In June 2019, the owners of a Panama City hotel that was managed by Trump's businesses, and carried the Trump brand, accused two companies, Trump Panama Hotel Management LLC and and Trump International Hotels Management LLC, of not paying taxes on their Panamanian earnings.

Panama's President José Raúl Mulino rejected former President Donald Trump's threat to reimpose U.S. control over the Panama Canal. Mulino asserted that the country's sovereignty over the canal is non-negotiable and that every square meter of the canal belongs to Panama.