"There’s people walking around that obviously do not have blonde hair – yet they do. I don’t think that’s weird either. It’s just whatever gets you through."

Gaffigan admitted to having trepidation to use the medication, a brand name for tirzepatide, after tipping the scales at 270 pounds.

Jim Gaffigan has always used his weight and love for eating as a punchline in his comedy, even going so far to title his 2013 memoir Dad Is Fat. But the 58-year-old recently lost a significant amount of weight with the anti-diabetic medication Mounjaro,

Jim Gaffigan is getting candid about his weight loss journey - and how deciding to use the drug Mounjaro has helped. "I was so paranoid that I was going to be nauseous that I kind of put it off, but then it kind of worked,

Jim Gaffigan has revealed using a weight-loss drug gave him a "better life". The comedian wants to challenge the stigma attached to using weight-loss injections after he successfully shed 50 pounds using the weight-loss drug Mounjaro.

Jim Gaffigan isn't ashamed to admit he jumped on the weight-loss medication bandwagon. In a new interview, the comedian revealed that when the scale hit 270 pounds last year, he decided to start taking Mounjaro,

Hulu Comedian Jim Gaffigan is the first to admit his weight has fluctuated over the years. After reaching 270 lbs., he decided to try medication — and has since lost 50 lbs. "I feel good," he tells PEOPLE.