Pacylex Pharmaceuticals Publishes a New Myristoylation Inhibitor Mechanism of Anti-Cancer Activity in Molecular Cancer Therapeutics ...

The regulation and remodeling of the tumor microenvironment (TME) are closely associated with how cancers typically progress ...

As Roche comes under competitive pressure on its breast cancer business, the Swiss company hopes a new drug will add a ...

immunogen = GST-fusion protein corresponding to residues 1-149 of human Akt ...

AstraZeneca's pan-AKT kinase inhibitor for breast cancer, which has shown efficacy in patients with hormone receptor positive, HER2-negative advanced breast cancer – regardless of their PIK3CA ...

By Pooja Toshniwal Paharia Breakthrough research sheds light on the genetic mutation behind aggressive prostate cancer. Study ...

There are similar data with EGFR monoclonal antibodies. Unlike in lung cancer ... PTEN = phosphatase and tension homolog deleted on chromosome 10; AKT = protein kinase B; STAT = signal transducer ...

No writing assistance was utilized in the production of this manuscript. Monoclonal antibodies are novel therapeutic agents used with great success in the treatment of rheumatoid arthritis (RA).

The advent of large-scale sequencing in both development and disease has identified large numbers of candidate genes that may be linked to important phenotypes. Validating the function of these ...

This useful study reports that the exogenous expression of the microRNA miR-195 can partially compensate in early B cell development for the loss of EBF1, one of the key transcription factors in B ...

Endothelial cells are major participants in and regulators of inflammatory reactions. Resting endothelial cells prevent coagulation, control blood flow and passage of proteins from blood into ...

Correspondence to Dr Chiara Bocelli-Tyndall, Department of Rheumatology, University Hospital Basel, Basel 4031, Switzerland; Chiara.Tyndall{at}usb.ch Objective Human bone marrow mesenchymal stromal ...