A 40-year-old man presented to the emergency department with a 5-day history of fevers, sore throat, fatigue, subjective ...

Tocilizumab -- an interleukin (IL)-6 receptor inhibitor -- was approved by the FDA in 2017 for the treatment of severe or ...

In preclinical models, the research team found that anakinra, a drug typically used for inflammatory conditions such as rheumatoid arthritis, can be repurposed to block harmful signals between ...

A 57-year-old woman with a 12-h history of fever and severe pain in her back, pelvis, and thighs attended our hospital. 24 h ...

Tumour necrosis factor-alpha (TNF-a) is a cytokine. A cytokine is a small protein. TNF-a is involved in inflammation. Drugs such as infliximab, etanercept, and adalimumab inhibit TNF activity and ...

Emapalumab-containing regimens showed positive outcomes in patients with rheumatologic disease–associated hemophagocytic ...

The new research, however, suggests that existing drugs such as baricitinib and anakinra can disrupt the malfunctioning immune response and finally allow damaged lungs to heal. Our collaboration ...

In preclinical models, the research team found that anakinra, a drug typically used for inflammatory conditions such as rheumatoid arthritis, can be repurposed to block harmful signals between ...

Antibodies that interfere with IL-1 function Anakinra interferes with IL-1 function and has established efficacy in RA, although its use is complicated by the need for daily injections with a high ...

In preclinical models, the research team found that anakinra, a drug typically used for inflammatory conditions such as rheumatoid arthritis, can be repurposed to block harmful signals between early ...