Cyclin-dependent kinase enzymes (CDKs) are of two types: cell cycle-regulating CDKs that participate in the progression of ...

Researchers developed novel genetic tools to trace, ablate, and manipulate p16^Ink4a+^ senescent cells, revealing their ...

The breakthrough research was conducted by scientists at the Indian Association for the Cultivation of Science (IACS), ...

Scientists have identified a promising new target for cancer treatment by activating a DNA repair enzyme called TDP1, ...

Scientists at the Indian Association for the Cultivation of Science (IACS), Kolkata, an autonomous institute of the ...

In a promising development for cancer treatment, researchers have pinpointed a new target by activating a DNA repair enzyme known as Tyrosyl-DNA phosphodiesterase 1 (TDP1).

The anti-tumour effects of Berberine, which possesses multiple pharmacological activities, have gained significant attention ...

Calcineurin fine tunes the balance between proliferation and differentiation of Notch-responsive progenitors in the pancreatic ducts to enable beta cell regeneration in zebrafish.

A recent discovery has found a possible avenue to improve human health by better understanding how to engineer human stem ...

The Boston-based firm just launched the first trial of a CDK12/13 inhibitor and is anticipating starting Phase III trials for a CDK7 inhibitor in 2026.

There are three interlocked, self-organized systems that constitute the whole cell cycle: the oscillator (temporal self-organization), the spindle and the nucleus (spatial self-organization), and ...