Microarray analysis identifies more chromosome abnormalities than traditional ... Currently, microarrays will not detect balanced rearrangements, but when combined with certain sequencing ...

Characteristics and outcome of patients with Philadelphia chromosome negative ... Kurzrock R, Bueso-Ramos CE, Kantarjian H, et al. BCR rearrangement-negative chronic myelogenous leukemia revisited. J ...

In genetics, chromosome translocation is a phenomenon that results in unusual rearrangement of chromosomes. This includes balanced and unbalanced translocation ...

In an experiment pertaining to chromosome engineering that was conducted in 2006, it was found that chromosome engineering can be effectively used as a method of identifying the causes of genetic ...

Dr. Kolibaba is Instructor of Medicine, Division of Hematology and Medical Oncology, and Dr. Druker is Associate Professor of Medicine, Division of Hematology and Medical Oncology, Department of ...

We identified a novel 291 kb chromosomal inversion involving chromosome 3p in affected family members. This inversion disrupts the VHL gene between exon 2 and exon 3 and is thereby responsible for the ...

bDepartment of Applied Science at the Swiss Federal Institute of Technology, Zurich, Switzerland Treatment options for patients with chronic myeloid leukaemia (CML) and other types of leukaemia ...

We classified a repertoire of integration patterns featured by complex genomic rearrangement. We also conducted a clustered regularly interspaced short palindromic repeat (CRISPR)-based ...

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