B-cell activating factor receptor (BAFF-R) chimeric antigen receptor (CAR) T-cell therapy incited cytotoxic effects on both ...

Umoja Biopharma, Inc. (Umoja), a transformative immunotherapy company creating off-the-shelf treatments that aim to extend the reach and effectiveness of CAR-T cell therapies in oncology and ...

The following is a summary of “Hematopoietic stem cell transplantation for CTLA-4 insufficiency across Europe: A European ...

Stimulating a key metabolic pathway in T cells can make them work more effectively against tumors when combined with immune ...

Elicera Therapeutics describes how CAR T cells armed with neutrophil-activatingprotein can improve cancer therapy by inducing ...

Managed Healthcare Executive provides C-suite executives at health plans and provider organizations with news, analysis, ...

The autoimmune response in AIH may be triggered by molecular mimicry, where T cells mistakenly attack host proteins. The presence of autoantibodies and antigen-specific cytotoxic T cells exacerbates ...

that acts as a barrier to infiltrating anti-tumor immune cells such as cytotoxic T lymphocytes (CTLs). In a new paper, published in Nature Cancer, first author Tharp and colleagues illuminate how the ...

Acute Myeloid Leukemia (AML) remains one of the most challenging hematological malignancies to treat, with relapse and refractory cases continuing to pose significant hurdles ...

In a collaborative interdisciplinary study, Michael Mitchell of the School of Engineering and Applied Science, Wei Guo of the School of Arts & Sciences, and Drew Weissman of the Perelman School of ...

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A first-of-its-kind study has measured the toxicity of several types of per- and polyfluoroalkyl substances (PFAS), better ...