Epigenetics, the study of changes in gene function that do not involve alterations to the DNA sequence, plays a pivotal role ...

Study reveals widespread dysregulation of transposable elements (TEs) in aging human brains with Alzheimer's disease, using ...

with changes in histone acetylation and methylation found in atherosclerotic tissues. Environmental exposure is a significant theme throughout the review. It discusses how factors such as air ...

The sequencing of the human genome at the turn of the 21st century was heralded as a monumental scientific achievement ...

At least 18 different forms of histone modification have been identified, most commonly at lysine (K) residues on histones H3 and H4 (Zhao and Garcia, 2015). Among these, acetylation, methylation, and ...

A research team, delving into the impact of excessive prenatal prednisone exposure (PPE) on fetal development, discovered ...

Keywords: human GI tract, gut microbiome, host genetics, host epigenetics, epi-transcriptomics, GI homeostasis, microbiome-derived metabolites, DNA methylation, histone acetylation Important Note: All ...

The N-terminal tails of histones are subject to multiple post-translational modifications — including phosphorylation, ubiquitination, acetylation ... landscape of histone-methylation regulation ...

Studies have shown that epigenetic therapies can reprogram histone modifications in DMG ... inhibit tumor cell growth by increasing H3K27 acetylation (H3K27ac) and decreasing H3K27 trimethylation ...

Studies have shown that epigenetic therapies can reprogram histone modifications in DMG ... inhibit tumor cell growth by increasing H3K27 acetylation (H3K27ac) and decreasing H3K27 trimethylation ...