Fever temperatures rev up immune cell metabolism, proliferation and activity, but they also—in a particular subset of T cells ...

Fever temperatures rev up immune cell metabolism, proliferation and activity, but they also -- in a particular subset of T cells -- cause mitochondrial stress, DNA damage and cell death, researchers ...

Flow cytometry, cell sorting, ELISA, mRNA-sequencing, RT-qPCR, western blot, and cell culture experiments were performed to evaluate the regulatory mechanism of ... CD107a) and cytokine secretion (IFN ...

Severe patients with COVID-19 may suffer from progressive pneumonia, acute respiratory distress syndrome and multiorgan failure due to hyperinflammation and a cytokine storm syndrome ... this antibody ...

One possible strategy for the treatment of T1D is to stimulate the regulatory arm of the immune response, i.e. to promote the function of tolerogenic dendritic cells (tolDC) and regulatory T cells ...

Northwestern Medicine scientists have discovered a new mechanism that controls a specialized group of T-cells, known as ...

It is long past time to fix the regulatory regime that created this ... The substantial profits both sides are fighting over weren’t derived from admirable business practices.

Tocilizumab -- an interleukin (IL)-6 receptor inhibitor -- was approved by the FDA in 2017 for the treatment of severe or ...

In the article, the researchers describe a potential new method involving administering regulatory T cells (Tregs) to enhance tissue healing. Following tissue injury, certain immune cells initiate ...

Research shows Fc–IL-4 revitalizes exhausted CD8+ T cells, boosting antitumor responses and highlighting the potential of ...