T-cell activation is a multistep process requiring T-cell receptor engagement by peptide-major histocompatibility complexes (Signal 1) coupled with CD28-mediated costimulation ... cells via a ...

The online forum, which is scheduled for 6 to 7:30 p.m. on Sept. 18, will feature U.S. House of Representatives candidates running for the CD3 seat in the November general election. The race includes ...

To aid in the production of desired phenotypes, CD3/CD28 active-release beads have been developed to add extra flexibility and further shorten the manufacturing process. This application note ...

T cell activation is an essential step in adoptive T cell therapies. This process generally uses anti-CD3 and anti-CD28 antibodies or CD3/CD28 antibody-conjugated magnetic beads, which activate T ...

Upon collection of peripheral blood leukapheresis products from patients, T cells are isolated, expanded using anti-CD3/CD28 co-stimulation and cytokine supplementation, transduced with a CAR-encoding ...