The latest updates on George Kittle’s injury status for Week 4 vs. the New England Patriots. Stay informed with our ...

San Francisco 49ers wide receiver Deebo Samuel is expected to play Sunday against the New England Patriots, a source told ...

Here are five keys the 49ers (1-2) must accomplish to avoid losing a third straight game Sunday when they host the New ...

The San Francisco 49ers face the New England Patriots at 1:05 p.m. PDT on Sunday, Sept. 29 at Levi’s Stadium in Santa Clara, ...

Do the San Francisco 49ers bounce back in Week 4? After a tough loss as road favorites to the Los Angeles Rams in Week 3, the 49ers are the biggest favorite on ...

The New England Patriots will look to avoid a third straight loss, following a 24-3 defeat at the hands of the New York Jets ...

SportsLine's model simulated New England Patriots vs. San Francisco 49ers 10,000 times and made its Week 4 NFL picks, ...

The San Francisco 49ers have dealt with significant injuries to key players including Christian McCaffrey, Deebo Samuel, and ...

Getting Kittle back out on the field will be massive for the 49ers as they look to stop the bleeding. He has been one of the ...

And Purdy would pass this test with flying colors, throwing for 292 yards and three touchdowns, ultimately losing the game 27-24 to the Los Angeles Rams. Fortunately, the 49ers should be getting some ...

San Francisco 49ers coach Kyle Shanahan views his team's low YAC numbers as a byproduct of unfortunate injuries.

The 49ers have begun the season 1-2 and blew a fourth-quarter lead last weekend against the Rams. Jauan Jennings has emerged ...