Myotonic dystrophy is an inherited muscular dystrophy causing muscle weakness and wasting. Excessive daytime sleepiness (hypersomnia) is a frequent complaint of people with myotonic dystrophy and is ...

Perineal HAase injection during the second stage of labour probably reduces swelling in the perineal area 24 hours after vaginal delivery when compared with placebo injection. More studies of high ...

Tacrolimus, cyclosporin, mycophenolate mofetil, and levamisole may reduce the risk of relapse in children with frequently relapsing nephrotic syndrome. Cyclophosphamide and chlorambucil compared with ...

In people with mild cognitive impairment, galantamine, compared to placebo, may make little to no difference in improving memory or the ability to do self-care activities. However, participants who ...

Using statins for the primary prevention of VTE may slightly reduce the incidence of VTE and all-cause mortality. However, this effect is likely too weak to be considered significant. Statin use may ...

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If you found this evidence helpful, please consider donating to Cochrane. We are a charity that produces accessible evidence to help people make health and care decisions. Papapanou M, Vaidakis D, ...

If you found this evidence helpful, please consider donating to Cochrane. We are a charity that produces accessible evidence to help people make health and care decisions.

to assess the benefits and harms of currently recommended regimens as the first-line therapy in high-risk people with chronic lymphocytic leukemia, using network meta-analysis Secondary objectives: to ...

Current evidence suggests that uterotonic agents (such as misoprostol and sulprostone) may result in little to no difference in the rates of manual removal of the placenta, and probably result in ...

En comparación con la práctica habitual (es decir, la notificación espontánea con o sin alguna capacitación de las unidades regionales de farmacovigilancia), evidencia de certeza baja indica que el ...