Opioids - Brorphine - Bluelight.org
361. Feb 22, 2022. #1. I note a new class of opioid. It contains 4 of the 5 key moieties of a strong opioid, an ideal biosteric minimum and a clear metabolic pathway. If you go back to the 60s, Janssen produced some closely related compounds. In that case, a figure of x450 pethidine (x45 M) was given but that p-Br is important in obtaining the ...
Miscellaneous - Is Ambien similar to a dissociative or psychedelic …
Apr 9, 2014 · Wikipedia said: Zolpidem (brand names Ambien, Ambien CR, Intermezzo, Stilnox, Stilnoct, Sublinox, Hypnogen and Zolsana) is a prescription medication used for the treatment of insomnia and some brain disorders. It is a short-acting nonbenzodiazepine hypnotic of the imidazopyridine class. I said I made a mistake.
Practical MXE replacement - Bluelight.org
Feb 2, 2022 · As you say< most likely the -OH metabolite. Of course, their ARE known bioisosteres of the phenolic moiety. Papers on 8CAC show that a carrboxamine (-CONH2) is almost equally active but interestingly, MP Wentland (the discoverer of 8CAC) actually used high-throughput screening to develop derivatives of the carboxamine that had much greater ...