Subgenomic mRNA - Wikipedia
WEBSubgenomic mRNA - Wikipedia. Subgenomic mRNA s are essentially smaller sections of the original transcribed template strand. 3' to 5' DNA or RNA. During transcription, the original template strand is usually read from the 3' to the 5' end from beginning to end.
SARS-CoV-2 Subgenomic RNAs: Characterization, Utility, and …
WEBSep 24, 2021 · SARS-CoV-2, the etiologic agent at the root of the ongoing COVID-19 pandemic, harbors a large RNA genome from which a tiered ensemble of subgenomic RNAs (sgRNAs) is generated. Comprehensive definition and investigation of these RNA products are important for understanding SARS-CoV-2 pathogenesis.
SARS-CoV-2 genomic and subgenomic RNAs in diagnostic …
WEBNov 27, 2020 · Here we show detection of SARS-CoV-2 subgenomic RNAs in diagnostic samples up to 17 days after initial detection of infection and provide evidence for their nuclease resistance and protection by...
Subgenomic RNAs and Their Encoded Proteins Contribute to the …
WEBNov 12, 2022 · This review focuses on the characteristics and functions of SARS-CoV-2 subgenomic RNAs and their encoded proteins and explores in depth the role of subgenomic RNAs in the replication and infection of host cells to provide important clues to the mechanism of COVID-19 pathogenesis.
The SARS-CoV-2 subgenome landscape and its novel ... - Cell Press
WEBIn this study, we employed NGS and Nanopore direct RNA-seq techniques to systematically characterize (1) the global and dynamic profiles of template-switching events and (2) the full-length subgenomes of SARS-CoV-2 in two …
Diagnostic usefulness of subgenomic RNA detection of viable …
WEBAug 13, 2021 · Our comparison of subgenomic RNA detection with symptom duration and SARS-CoV-2 culture positivity provides a significant advancement on the transmissibility-based approach beyond the detection of SARS-CoV-2 genomic RNA, and warrants further studies on the development of better diagnostic strategy.
Accurate detection and quantification of SARS-CoV-2 genomic …
WEBOct 22, 2021 · In our study, we demonstrated that a significant reduction of subgenomic RNAs species is consistently detectable in samples with a low content of gRNA.
SARS-CoV-2 Subgenomic RNAs: Characterization, Utility, and …
WEBSep 24, 2021 · SARS-CoV-2, the etiologic agent at the root of the ongoing COVID-19 pandemic, harbors a large RNA genome from which a tiered ensemble of subgenomic RNAs (sgRNAs) is generated. Comprehensive definition and investigation of these RNA products are important for understanding SARS-CoV-2 pathogenesis.
The SARS-CoV-2 subgenome landscape and its novel regulatory features
WEBMay 20, 2021 · CoVs are known to generate negative subgenomes (subgenomic RNAs [sgRNAs]) through transcription-regulating sequence (TRS)-dependent template switching, but the global dynamic landscapes of coronaviral subgenomes and …
SARS-CoV-2 Subgenomic RNAs: Characterization, Utility, and …
WEBSep 24, 2021 · SARS-CoV-2, the etiologic agent at the root of the ongoing COVID-19 pandemic, harbors a large RNA genome from which a tiered ensemble of subgenomic RNAs (sgRNAs) is generated. Comprehensive definition and investigation of these RNA products are important for understanding SARS-CoV-2 pathogenesis.
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