Unraveling the Role of the Apical Papilla During Dental Root …
WEBMay 6, 2021 · The apical papilla is a stem cell rich tissue located at the base of the developing dental root and is responsible for the progressive elongation and maturation of the root.
Stem Cells from the Apical Papilla (SCAPs): Past, Present ... - MDPI
WEBJul 20, 2023 · Endogenous stem cells residing in the apical papilla, named stem cells from the apical papilla (SCAPs), have been intensively investigated due to their critical roles in pulp regeneration and root redevelopment. The present review summarizes advances in the field of SCAPs studies and discusses the challenges that need to be further addressed.
Apical Papilla - an overview | ScienceDirect Topics
WEBThe apical papilla is a padlike tissue at the apex of immature root (Degistirici et al., 2008; Sonoyama et al., 2008). Further apical to the apical papilla, there is a layer of soft tissue termed periapical follicle, which is the developing …
Unraveling the Role of the Apical Papilla During Dental Root ... - PubMed
WEBMay 6, 2021 · In this review, we will focus on the architecture of the apical papilla and describe the specific SCAP signaling pathways involved in root maturation. Furthermore, we will explore the heterogeneity of the SCAP phenotype within the tissue and determine their micro-environmental interaction.
Stem Cells from the Apical Papilla: A Promising Source for Stem …
WEBJan 29, 2019 · Stem cells from the apical papilla (SCAPs) residing in the apical papilla of immature permanent teeth represent a novel population of dental MSCs that possesses the properties of high proliferative potential, the self-renewal ability, and low immunogenicity [1].
WEBmultipotent stem cells of the apical papilla (SCAP) are extensively studied in cell culture since they demonstrate a high capacity for osteogenic, adipogenic, and chondrogenic differentiation and are thus an attractive stem cell source for stem cell-based therapies.
Role and application of stem cells in dental regeneration: A ...
WEBFeb 22, 2021 · Stem cells from apical papilla. The stem cells from the apical papilla (SCAPs) belong to a unique SC line locating at the apical tissues of the growing tooth roots when at least two-thirds of the root have formed (Lin …
WEBOct 21, 2023 · Toll-like receptors (TLRs) are crucial in recognizing pathogen-associated molecular patterns. Stem cells of the apical papilla (SCAP) are required for normal dental development and are intimately involved in the reparative and regenerative capacity of developing teeth.
Differentiation Potential of Dental Papilla, Dental Pulp, and Apical ...
WEBMay 1, 2010 · The molecular, cellular, and functional characteristics of the apical papilla should be investigated systematically to elucidate whether apical papilla is an odontogenic neural crest–derived ectomesenchymal cell population and whether it …
Survival of the Apical Papilla and Its Resident Stem Cells in ... - PubMed
WEBIntroduction: Apical papilla represents a source of an enriched mesenchymal stem cell (MSC) population (stem cells of the apical papilla [SCAPs]) that modulates root development and may participate in regenerative endodontic procedures in immature teeth with pulp necrosis.