Efficacy of long-term maintenance therapy with mycophenolate …
WEBOct 28, 2014 · Tapering: mycophenolate mofetil dosage remains unchanged for the first year followed by dose reduction in the second year, in the absence of relapse or partial remission fulfillment.
Lupus nephritis: Initial and subsequent therapy for focal or diffuse ...
WEBJul 31, 2024 · The treatment of focal or diffuse LN has two main components: initial therapy with antiinflammatory and immunosuppressive agents to slow or halt kidney injury, followed by long-term subsequent immunosuppressive therapy to control the chronic autoimmune processes of systemic lupus erythematosus and to foster repair of damaged nephrons.
Mycophenolate: Overview of use and adverse effects in the ... - UpToDate
WEBMay 21, 2024 · Mycophenolate (also known as mycophenolic acid [MPA]), a powerful inhibitor of lymphocyte proliferation, has been used since the early 1990s for the prevention of acute allograft rejection.
Mycophenolate versus Azathioprine as Maintenance Therapy …
WEBNov 17, 2011 · We conducted a prospective, randomized, double-blind, double-dummy, phase 3 study comparing mycophenolate mofetil (CellCept, Roche) with azathioprine (Imuran, GlaxoSmithKline) for the maintenance...
Efficacy and safety of mycophenolate mofetil in the treatment of ...
WEBSince 2001, many retrospective reviews and small prospective case series 68, 73 – 88 have assessed the role of MMF in SSc-ILD, providing encouraging results in terms of improvement or stability in lung function and symptoms as well as a good safety profile.
Mycophenolate Mofetil or Intravenous Cyclophosphamide for …
WEBNov 24, 2005 · Patients received prednisone at a dose of 1 mg per kilogram of body weight per day, with tapering by 10 to 20 percent at one-week or two-week intervals, on the basis of clinical improvement.
WEBor azathioprine) taper Table S28. Patients with proliferative lupus nephritis—maintenance: leflunomide versus maintenance: azathioprine Appendix D. Data supplement—Additional SoF tables developed as part of the evidence review Table S29. Patients with proliferative lupus nephritis—induction: calcineurin inhibitors versus induction ...
Can mycophenolate mofetil be tapered safely in myasthenia …
WEBTapering MMF appears safe after years of disease stability. Reducing the dose at a dose of only 500 mg/day every 12 months is recommended.
Mycophenolate Mofetil for First-Line Treatment of Immune ...
WEBSep 1, 2021 · The addition of mycophenolate mofetil to a glucocorticoid for first-line treatment of immune thrombocytopenia resulted in greater response and a lower risk of refractory or relapsed immune...
Mycophenolate mofetil withdrawal in patients with systemic lupus ...
WEBJan 29, 2024 · Maintenance therapy withdrawal was associated with a higher risk of severe SLE flares. The WIN-Lupus trial was limited to patients with lupus nephritis, a fifth of whom were receiving azathioprine and not mycophenolate mofetil as maintenance immunosuppressive therapy. Added value of this study.