A Novel Gd-DTPA-conjugated Poly(L-γ-glutamyl-glutamine
WEBJun 19, 2017 · In this study, poly (L-γ-glutamyl-glutamine)-paclitaxel (PGG-PTX), as a model polymer, was chemically conjugated with Gd-DTPA (Gd-diethylenetriaminepentaacetic acid), a T1-contrast agent of...
WEBIn this study, poly(L-γ-glutamyl-glutamine)-paclitaxel (PGG-PTX), as a model polymer, was chemically conjugated with Gd-DTPA (Gd-diethylenetriaminepentaacetic acid), a T1-contrast agent...
A Novel Gd-DTPA-conjugated Poly(L-γ-glutamyl-glutamine) …
WEBJun 19, 2017 · In this study, poly (L-γ-glutamyl-glutamine)-paclitaxel (PGG-PTX), as a model polymer, was chemically conjugated with Gd-DTPA (Gd-diethylenetriaminepentaacetic acid), a T 1 -contrast agent of MRI, to prepare a Gd-DTPA-conjugated PGG-PTX (PGG-PTX-DTPA-Gd) delivery system used for tumor theranostics.
Polymeric Conjugates of Gd3+−Diethylenetriaminepentaacetic …
WEBJul 29, 1997 · Macromolecular conjugates of dextran and diethylenetriaminepentaacetic acid (DTPA), aimed to complex gadolinium, were synthesized to obtain contrast agents for nuclear magnetic resonance imaging with good paramagnetic properties and long intravascular persistence.
A Novel Gd-DTPA-conjugated Poly(L-γ-glutamyl-glutamine ... - PubMed
WEBJun 19, 2017 · In this study, poly (L-γ-glutamyl-glutamine)-paclitaxel (PGG-PTX), as a model polymer, was chemically conjugated with Gd-DTPA (Gd-diethylenetriaminepentaacetic acid), a T 1 -contrast agent of MRI, to prepare a Gd-DTPA-conjugated PGG-PTX (PGG-PTX-DTPA-Gd) delivery system used for tumor theranostics.
Gd-DTPA-loaded polymer-metal complex micelles with high
WEBGd-DTPA-loaded polymeric micelles (Gd-DTPA/m) showed a hydrodynamic diameter of 45 nm and a core size of 22 nm. Confining Gd-DTPA inside the core of the micelles increased the relaxivity of Gd-DTPA more than 13 times (48 mM (-1) s (-1)).
Dynamics of tumor imaging with Gd‐DTPA—polyethylene glycol polymers ...
WEBPolymers smaller than 20 kd displayed dynamics similar to those of the freely diffusible agent Gd‐DTPA. Above the 20 kd threshold, tumor enhancement was more rapid for smaller polymers. The authors conclude that the 21.9‐kd Gd‐DTPA‐PEG polymer is best suited for clinical MR imaging.
[PDF] A Novel Gd-DTPA-conjugated Poly(L-γ-glutamyl-glutamine ...
WEBJun 19, 2017 · In this study, poly(L-γ-glutamyl-glutamine)-paclitaxel (PGG-PTX), as a model polymer, was chemically conjugated with Gd-DTPA (Gd-diethylenetriaminepentaacetic acid), a T1-contrast agent of MRI, to prepare a Gd-DTPA-conjugated PGG-PTX (PGG-PTX-DTPA-Gd) delivery system used for tumor theranostics.
High relaxivity linear Gd(DTPA)-polymer conjugates: the role of ...
WEBA series of linear copolymers of DTPA-class Gd3+ conjugates, linked by alpha, omega-alkyldiamides with a varying number (n) of methylenes separating the amide function, were synthesized.
High relaxivity linear Gd(DTPA)‐polymer conjugates: The role of ...
WEBDec 12, 2005 · A series of linear copolymers of DTPA-class Gd 3+ conjugates, linked by α,ω-alkyldiamides with a varying number ( n) of methylenes separating the amide function, were synthesized. Surprisingly, their relaxivities at all fields increased with increasing n.