Renin-Angiotensin-Aldosterone System (RAAS) - Cleveland Clinic
WEBThe renin–angiotensin–aldosterone system (RAAS) is a critical regulator of blood volume and systemic vascular resistance on a long-term basis. The baroreceptor reflex, on the other hand, responds in a short-term manner to decreased blood pressure.
Renin-angiotensin-aldosterone system inhibitors - AMBOSS
WEBRenin-angiotensin-aldosterone system (RAAS) inhibitors are a group of drugs that act by inhibiting the renin-angiotensin-aldosterone system (RAAS) and include angiotensin-converting enzyme inhibito...
Renin–angiotensin system - Wikipedia
WEBThe renin-angiotensin system (RAS), or renin-angiotensin-aldosterone system (RAAS), is a hormone system that regulates blood pressure, fluid, and electrolyte balance, and systemic vascular resistance.
Advances in understanding the renin-angiotensin-aldosterone system ...
WEBMar 21, 2017 · There are well-established drugs that interfere with the renin-angiotensin-aldosterone system (RAAS) at several sites, including (1) angiotensin-converting enzyme inhibitors (ACEIs), (2) angiotensin II type I (AT 1) receptor blockers (ARBs), (3) direct renin inhibitors (DRIs), (4) mineralocorticoid receptor antagonists (MRAs), and even (5) beta ...
Renin-angiotensin system inhibition in the treatment of ... - UpToDate
WEBMay 30, 2023 · Inhibitors of the renin-angiotensin system (RAS), particularly angiotensin-converting enzyme (ACE) inhibitors and angiotensin II receptor blockers (ARBs), are commonly used in the treatment of hypertension.
Novel RAAS agonists and antagonists: clinical applications and ...
WEBFeb 10, 2015 · The renin–angiotensin–aldosterone system (RAAS) regulates blood pressure homeostasis via multiple mechanisms that act on a variety of organs. The development of drugs that target RAAS components is an active area of research.
Physiology, Renin Angiotensin System - StatPearls - NCBI Bookshelf
WEBMar 12, 2023 · Overactivation of the renin-angiotensin-aldosterone system has been implicated in the pathogenesis of various cardiovascular and renal diseases. RAAS is also implicated in the pathogenesis of primary hypertension. This has been proven by using medications that block the RAAS at different steps.
Drugs targeting the renin–angiotensin–aldosterone system
WEBAug 1, 2002 · Approved drugs that act on the RAAS that are discussed here include ACE inhibitors, AT 1 -receptor blockers (ARBs) and aldosterone-receptor antagonists (ARAs). These agents have been shown to be...
Novel RAAS agonists and antagonists: clinical applications and ... - Nature
WEBFeb 10, 2015 · Renin–angiotensin–aldosterone system (RAAS) blockade with an angiotensin converting enzyme inhibitor or an angiotensin receptor blocker provides a 20% relative risk reduction for the...
Overview of the renin-angiotensin system - UpToDate
WEBSep 27, 2023 · The renin-angiotensin system (RAS) plays a crucial role in the regulation of renal, cardiac, and vascular physiology, and its activation is central to many common pathologic conditions including hypertension, heart failure, and renal disease.