The Developmental Mechanics of Cell Specification
WEBModes of cell type specification and their characteristics. Autonomous specification (mosaic development). (A-C) Differentiation of trochoblast (ciliated) cells of the mollusc Patella. (A) 16-cell stage seen from the side; the presumptive trochoblast cells are shaded. (B) 48-cell stage. (C) Ciliated larval stage, (more...)
Cell fate determination - Wikipedia
WEBWithin the field of developmental biology, one goal is to understand how a particular cell develops into a final cell type, known as fate determination. Within an embryo, several processes play out at the cellular and tissue level to create an organism.
Mechanisms of human embryo development: from cell fate to …
WEBJul 7, 2020 — Summary: Dissecting the mechanisms behind cell fate specification, tissue shape changes and their mutual regulation generates an integrated understanding of embryogenesis. Recent technological advances now …
Coordination of Morphogenesis and Cell-Fate Specification in ...
WEBSep 25, 2017 — Understanding the crosstalk between tissue-scale mechanics and cell-fate specification is essential to uncover the key design principles that regulate robust tissue patterning during development.
Specification and epigenetic programming of the human germ …
WEBAug 30, 2016 — Regulation of pluripotency and early post-implantation embryonic development have diverged between humans and mice, which might affect the mechanism of primordial germ cell (PGC) specification.
How a cell decides its own fate: a single-cell view of molecular ...
WEBDec 12, 2021 — Recently developed single-cell omics techniques have started to provide an unprecedented, comprehensive view of the molecular changes during cell-type specification and promise to reveal the underlying gene regulatory mechanism.
Cell fate specification and differentiation in the adult mammalian ...
WEBSep 21, 2020 — Identifying the factors and mechanisms that control cell fate in the intestine has enabled the production of organoids that are enriched in specific cell types, which could be used for drug...
The Importance of Being Specified: Cell Fate Decisions and Their …
WEBOct 13, 2017 — Cell fate specification, and ultimately the characteristics that give a cell its identity, are thereby governed by a regulatory network of specific transcription factors (TFs) that include the effectors of cell signaling cascades and …
Evolutionarily Distinctive Transcriptional and Signaling ... - Cell Press
WEBOct 5, 2017 — The mechanism for germ cell specification has been classified into two major modes: one is through the inheritance by the blastomeres of preformed germ plasm in oocytes and the other is through the induction in pluripotent embryonic cells by signaling molecules (Extavour and Akam, 2003). Germ cell specification in …
Cell Specialization: Mechanisms, Examples, & Significance
WEBOct 26, 2022 — Cell specialization is the process by which cells evolve to cells with specific functions. Let's explore its mechanisms, examples and significance here.